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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg Product Name Trametiglue Synonyms CAS

SKU 96861931846
4.2
USD495.00 USD534.00

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Description

Product Name Trametiglue Synonyms CAS Number 2666940-97-0 Related CAS Molecular Formula C25H24FIN6O5S Molecular Weight 666

Product Name Pomalidomide-PEG2-C2-Br Synonyms Pomalidomide-4'-PEG2-C2-Br CAS Number n/a Related CAS Molecular Formula C19H22BrN3O6 Molecular Weight 468

Ex/Em = 553/577 nm

146 SMILES BrC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg Product Name Trametiglue Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl

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