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OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA click the introduction of the charged

SKU 95138254938
4.8
USD450.00 USD484.00

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Description

the introduction of the charged sulfonate group minimally altered the excitation and emission profiles compared to the non-sulfonated TMR-d12 (HTL:

6-TAMRA has been a widely used fluorophore for preparing bioconjugates

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H87N7O24 Molecular Weight 1266

potentially reducing interference with the tagged protein’s function

OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA click the introduction of the chargedOSu PEG4 vc PAB DMEA Duocarmycin SA is a cleavable ADC druglinker conjugate that couples the potent antitumor antibiotic Duocarmycin SA to an OSu PEG4 vc PAB DMEA linker. The DNA? modifying agents such as duocarmycin are increasingly used in the development of antibody? drug conjugates (ADCs), where they serve as highly potent cytotoxic payloads. Designed for ADC research, this construct supports efficient antibody conjugation, PEG4? enhanced

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