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Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP chelator CC-3060 is a Cereblon modulator

SKU 93487658031
4.9
USD345.00 USD391.00

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Description

CC-3060 is a Cereblon modulator and promotes ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF1 zinc finger domains

33 SMILES OCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG4-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H51N7O9S Molecular Weight 733

265 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP chelator CC-3060 is a Cereblon modulatorSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as

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