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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor fluorescent labeling

SKU 88742756336
4.4
EUR445.00 EUR489.00

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Description

fluorescent labeling

684 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1

349 Purity (HPLC) >= 95% Solubility DMSO

Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C49H88N8O19 Molecular Weight 1093

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor fluorescent labelingSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation

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