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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:5mg and an excitation maximum that

SKU 88472587581
4.8
USD445.00 USD488.00

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Description

and an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN2CCNCC2)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C90H137N13O26 Molecular Weight 1817

Product Name N-(3-bromophenyl)acetamide-d3 Synonyms N-(3-bromophenyl)(²H3)acetamide CAS Number n/a Related CAS Molecular Formula C8H8BrNO Molecular Weight 217

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:5mg and an excitation maximum thatSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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