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Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 391 SMILES OCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

SKU 8263169872
4.8
EUR445.00 EUR488.00

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Description

391 SMILES OCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-propargyl Synonyms CAS Number 911197-00-7 Related CAS Molecular Formula C31H55N5O7 Molecular Weight 609

916 Purity (HPLC) >= 95% Solubility DMSO

Product Name 4-(methoxy-d3)benzaldehyde Synonyms 4-(²H3)methoxybenzaldehyde CAS Number 342611-04-5 Related CAS Molecular Formula C8H8O2 Molecular Weight 139

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 391 SMILES OCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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