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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP biotin Product Name Phthalimidinoglutarimide-propargyl-C1-amine HCl Synonyms

SKU 82124436642
4.3
USD345.00 USD388.00

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Description

Product Name Phthalimidinoglutarimide-propargyl-C1-amine HCl Synonyms Phthalimidinoglutarimide-4'-propargyl-C1-amine HCl CAS Number 2138440-40-9 Related CAS Molecular Formula C17H18ClN3O3 Molecular Weight 347

N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C8H9ClFN Molecular Weight 179

Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CAS Number 819869-77-7 Related CAS Molecular Formula C32H55N5O10 Molecular Weight 669

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP biotin Product Name Phthalimidinoglutarimide-propargyl-C1-amine HCl SynonymsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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