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The water soluble 5(6)-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group
References
972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Taselisib Synonyms CAS Number 1282512-48-4 Related CAS Molecular Formula C24H28N8O2 Molecular Weight 460
Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg The water soluble 5(6)-FAM PEG3SOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
