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Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CAS Number Related CAS Molecular Formula C24H44N8O10 Molecular Weight 604
Product Name Pomalidomide-CO-C6-Br Synonyms Pomalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H22BrN3O5 Molecular Weight 464
Product Name Fmoc-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C43H58N6O11 Molecular Weight 834
with the fluorophore removable by treatment with 100 mM sodium 2-mercaptoethanesulfonate (MESNA)
Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE ala Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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