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Fmoc-Val-Cit-PAB-PNP Size:100mg 02 Purity (HPLC) >= 95%

SKU 75449697317
4.8
USD90.00 USD128.00

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Ships within 48 hours · Estimated delivery Aug 20 - Aug 25

Description

02 Purity (HPLC) >= 95% Solubility DMSO

Product Name Biotin-PEG3-acid Synonyms CAS Number 252881-76-8 Related CAS Molecular Formula C19H33N3O7S Molecular Weight 447

Product Name DOTA-PEG3-C2-amine Synonyms CAS Number 2866181-79-3 Related CAS Molecular Formula C24H46N6O10 Molecular Weight 578

92 Purity (HPLC) >= 95% Solubility DMSO

Fmoc-Val-Cit-PAB-PNP Size:100mg 02 Purity (HPLC) >= 95%Fmoc Val Cit PAB PNP is a cleavable ADC linker used in antibodydrug conjugate (ADC) development, designed to enable enzyme responsive payload release in tumor targeted applications. The ValCit dipeptide is optimized for cathepsin B cleavage in lysosomal environments, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. The p nitrophenyl (PNP) group functions as an efficient leaving group for conjugation to

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