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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Size:100mg Nishiguchi

SKU 75280635101
4.1
USD195.00 USD223.00

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Description

Nishiguchi

Product Name Thalidomide-O-acetamido-C2-acid Synonyms Thalidomide-4'-O-acetamido-C2-acid CAS Number n/a Related CAS Molecular Formula C18H17N3O8 Molecular Weight 403

213 Purity (HPLC) >= 95% Solubility DMSO

S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9 Related CAS Molecular Formula C34H50N4O10S Molecular Weight 706

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Size:100mg NishiguchiSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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