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and radiotherapeutic agents
Biochemistry
E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15
Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H111FN12O28 Molecular Weight 1767
MC-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP click and radiotherapeutic agentsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be
