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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room Temperature

SKU 70720177366
4.1
USD445.00 USD484.00

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Ships within 48 hours · Estimated delivery Aug 8 - Aug 13

Description

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Lenalidomide-5'-CO-C3-alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353

Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493

915 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room TemperatureSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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