Thalidomide-O-C5-amine Pomalidomide 57 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCCN=[N]#N)=[N+](C)C)=C1

57 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCCN=[N]#N)=[N+](C)C)=C1

61 SMILES [2H]C([2H])([2H])NC1=C(Cl)C=C(F)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

665 SMILES OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

[O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=[OH+])NCCN1C(=O)C=CC1=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Thalidomide-O-C5-amine Pomalidomide 57 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCCN=[N]#N)=[N+](C)C)=C1Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal amine. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand. Product Name: Thalidomide O C5 amine Synonyms: 1H ? Isoindole ? 1,? 3(2H)? ? dione, 4 ?[(5 ? aminopentyl)? oxy]? ? 2 ?(2,? 6 ? dioxo ? 3 ? piperidinyl)? CAS Number: 2307477 23 0 Molecular Formula: C18H22ClN3O5 Molecular