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Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE m-peg8-pab Journal of Hematology & Oncology

SKU 68432014612
4.8
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Description

Journal of Hematology & Oncology 2021

Product Name CP-Vbn Synonyms SNAP2-Vbn CAS Number Related CAS Molecular Formula C21H19ClN4O2 Molecular Weight 394

12 Purity (HPLC) >= 95% Solubility DMSO

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE m-peg8-pab Journal of Hematology & OncologySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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