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Azide-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE peg 268 SMILES OC(=O)COC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

SKU 6741286017
4.2
USD445.00 USD493.00

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Description

268 SMILES OC(=O)COC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Keramatnia

Product Name BG-N3 Synonyms N-(4-((2-Amino-9H-purin-6-yloxy)methyl)benzyl)-2-azidoacetamide CAS Number Related CAS Molecular Formula C15H15N9O2 Molecular Weight 353

418 SMILES OCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE peg 268 SMILES OC(=O)COC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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