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ChemBioChem
Compound AN2 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
Product Name 5-Hydroxythalidomide Synonyms CAS Number 64567-60-8 Related CAS Molecular Formula C13H10N2O5 Molecular Weight 274
168 SMILES [H]C(=O)C1=CC=C(OC([2H])([2H])[2H])C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
NRX-1532 ketone ChemBioChemNRX 1532 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 1532 Synonyms CAS Number n a Related CAS Molecular Formula C16H11F3N4O2 Molecular Weight 348. 285 SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=CC=NN2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid
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