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DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE deuterium-labeled-amine S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS Number

SKU 65639436696
4.5
EUR445.00 EUR493.00

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Description

S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS Number 2375432-97-4 Related CAS Molecular Formula C35H56ClN5O9S Molecular Weight 758

Product Name BG-SulfoCy3 Synonyms SNAP-SulfoCy3 CAS Number Related CAS Molecular Formula C43H48N8O8S2 Molecular Weight 869

897 Purity (HPLC) >= 95% Solubility DMSO

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB Synonyms CAS Number Related CAS Molecular Formula C50H66N6O11 Molecular Weight 927

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE deuterium-labeled-amine S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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