Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde 68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCC#C)C(C)(C)C)C=C1 Purity (HPLC)

68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name: 6-FAM alkyne Synonyms: 6-carboxyfluorescein

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

6-SiR-CA CAS Number Related CAS Molecular Formula C37H48ClN3O5Si Molecular Weight 678

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde 68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCC#C)C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,