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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor 415 Purity (HPLC) >= 95%

SKU 64416407419
4.1
EUR345.00 EUR387.00

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Ships within 48 hours · Estimated delivery Aug 19 - Aug 24

Description

415 Purity (HPLC) >= 95% Solubility DMSO

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C38H54N10O14 Molecular Weight 874

Contains an E3 ligase ligand with PEG linker and terminal alcohol

Product Name Phthalimidinoglutarimide-C4-Br Synonyms Phthalimidinoglutarimide-4'-C4-Br CAS Number n/a Related CAS Molecular Formula C17H19BrN2O3 Molecular Weight 379

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor 415 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine

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