Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester 94 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC)

94 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The red-fluorescent Lissamine rhodamine B C2 maleimide is a thiol reactive dye

Product Name: Lissamine rhodamine B C2 maleimide Synonyms: Sulforhodamine B C2 maleimide CAS Number: 1800246-48-3 Molecular Formula: C33H36N4O8S2 Molecular Weight: 680

Product Name Tram-bo Synonyms CAS Number n/a Related CAS Molecular Formula C47H46BF3IN9O7 Molecular Weight 1043

Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester 94 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker