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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan chemical 99 SMILES Cl

SKU 59071217559
4.5
EUR495.00 EUR541.00

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Description

99 SMILES Cl

The red-fluorescent Lissamine Rhodamine B Ethylenediamine is a mixture of isomers

84 SMILES Cl

22 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan chemical 99 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,

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