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DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9

SKU 5889665728
4.1
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Description

S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9 Related CAS Molecular Formula C27H34N4O5S Molecular Weight 526

NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

The payload is monomethyl auristatin E (MMAE)

Product Name tert-butyl N-{2-[4-(3-aminopropyl)piperazin-1-yl]ethyl}carbamate Synonyms CAS Number 2719062-98-1 Related CAS Molecular Formula C14H30N4O2 Molecular Weight 286

DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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