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Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan ether Product Name Thalidomide-O-PEG6-OH Synonyms Thalidomide-4'-O-PEG6-OH

SKU 58288044516
4.3
USD495.00 USD525.00

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Description

Product Name Thalidomide-O-PEG6-OH Synonyms Thalidomide-4'-O-PEG6-OH CAS Number 2484091-06-5 Related CAS Molecular Formula C25H34N2O11 Molecular Weight 538

Product Name DOTA-tris(t-Bu)ester-C2-amine Synonyms CAS Number 173308-19-5 Related CAS Molecular Formula C30H58N6O7 Molecular Weight 614

559 SMILES NCCCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

British Journal of Pharmacology n/a

Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan ether Product Name Thalidomide-O-PEG6-OH Synonyms Thalidomide-4'-O-PEG6-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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