Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE click 78 SMILES: Cl

78 SMILES: Cl

Contains cereblon ligand Thalidomid and 5'-substituted heterocyclic linker

Readily excited by the 546 nm spectral line from mercury-arc lamps used in fluorescent microscopes

26 SMILES CC1(N)CCN(CC1)C1=CN=C(C(N)=N1)C1=C(Cl)C(Cl)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE click 78 SMILES: ClSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The