Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate Synonyms

Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C23H48N6O3 Molecular Weight 456

61 SMILES [2H]C([2H])([2H])NC1=C(Cl)C=C(F)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

preventing it from forming a covalent bond with the Halo-tag protein

Product Name Rapamycin-LC-fluorescein Synonyms C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin CAS Number 1263034-82-7 Related CAS Molecular Formula C80H105N3O21 Molecular Weight 1444

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is