MC-Val-Cit-PAB(m-PEG8)-MMAE carboxylic acid Product Name Phthalimidinoglutarimide-C7-OH Synonyms Phthalimidinoglutarimide-4'-C7-OH

Product Name Phthalimidinoglutarimide-C7-OH Synonyms Phthalimidinoglutarimide-4'-C7-OH CAS Number n/a Related CAS Molecular Formula C20H26N2O4 Molecular Weight 358

68 Purity (HPLC) >= 95% Physical Appearance Orange solid Optical Properties Abs/Em Maxima: 553/580 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CA-TMR has been used for tracking protein localization

91 Purity (HPLC) >= 95% Physical Appearance Orange Solid Optical Properties Abs/Em Maxima: 502/511 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MC-Val-Cit-PAB(m-PEG8)-MMAE carboxylic acid Product Name Phthalimidinoglutarimide-C7-OH Synonyms Phthalimidinoglutarimide-4'-C7-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate