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Product Name SiR-NHS Synonyms 6-SiR-NHS CAS Number 1808181-14-7 Related CAS N/A Molecular Formula C31H31N3O6Si Molecular Weight 569
294 Purity (HPLC) >= 95% Solubility DMSO
which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM
[2H]C([2H])([2H])N(CCNC)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg Product Name SiR-NHS Synonyms 6-SiR-NHSSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by
