Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Size:25mg Product Name DOTA-C4-propanamido-maleimide Synonyms CAS

Product Name DOTA-C4-propanamido-maleimide Synonyms CAS Number 1018474-54-8  Related CAS Molecular Formula C27H43N7O10 Molecular Weight 625

5 SMILES CC(C)(C)OC(=O)N1CCN(CCN2CCN(CCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-PEG1-C2-acid Synonyms Thalidomide-4'-O-PEG1-C2-acid CAS Number n/a Related CAS Molecular Formula C18H18N2O8 Molecular Weight 390

82 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Size:25mg Product Name DOTA-C4-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para