DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) mal-propionyl-dap-m-PEG4 182 SMILES [2H]C([2H])([2H])OC1=C(C(C)=CC=C1)N(=O)=O Purity (HPLC)

182 SMILES [2H]C([2H])([2H])OC1=C(C(C)=CC=C1)N(=O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

496 SMILES OCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

203 Purity (HPLC) >= 95% Solubility DMSO

NCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) mal-propionyl-dap-m-PEG4 182 SMILES [2H]C([2H])([2H])OC1=C(C(C)=CC=C1)N(=O)=O Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through