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CA-DOTA-tris(t-Bu) AHPC Contains an E3 ligase ligand

SKU 45791931232
4.2
USD145.00 USD173.00

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Ships within 48 hours · Estimated delivery Aug 18 - Aug 23

Description

Contains an E3 ligase ligand substituted with amine

Product Name Thalidomide-C3-PEG1-C2-Br Synonyms Thalidomide-4'-C3-PEG1-C2-Br CAS Number n/a Related CAS Molecular Formula C20H23BrN2O6 Molecular Weight 467

SHP099 suppresses RAS–ERK signalling to inhibit the proliferation of receptor-tyrosine-kinase-driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models

367 SMILES OCCCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CA-DOTA-tris(t-Bu) AHPC Contains an E3 ligase ligandHaloTag is a self labeling protein derived from the haloalkane dehalogenase DhaA from Rhodococcus rhodochrous. Its active site reacts with chloroalkane substrates to form an irreversible bond. The covalent linkage between the HaloTag ligand and HaloTag protein enables rapid isolation and purification. CA DOTA tris(t Bu) can be used to attach DOTA moiety to protein. DOTA has been used in many different diagnostic and therapeutic applications, such as

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