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Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg Product Name DOTA-PEG2-C2-amine Synonyms CAS

SKU 45705109643
4.5
EUR445.00 EUR477.00

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Description

Product Name DOTA-PEG2-C2-amine Synonyms CAS Number 2866181-83-9 Related CAS Molecular Formula C22H42N6O9 Molecular Weight 534

Massarotti

031 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The excitation and emission wavelengths of rhodamine 6G fall between those of fluorescein and tetramethylrhodamine derivatives

Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg Product Name DOTA-PEG2-C2-amine Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers

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