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Val-Cit-PAB(m-PEG4) Size:25mg It promotes degradation of Aiolos

SKU 43645888286
4.6
USD245.00 USD290.00

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Description

It promotes degradation of Aiolos and Ikaros proteins

Pure 6-isomer

525 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCC#C)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

also referred to as the Cu(I)-catalyzed free click reaction

Val-Cit-PAB(m-PEG4) Size:25mg It promotes degradation of AiolosSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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