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Product Name CA-Vbn Synonyms Vinylbenzoyl-Halo
Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C45H59N11O14 Molecular Weight 978
Product Name CP-CPY Synonyms SNAP2-CPY CAS Number Related CAS Molecular Formula C40H39ClN6O4 Molecular Weight 703
O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCN(CCN2CCNCC2)CC1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only
Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name CA-Vbn Synonyms Vinylbenzoyl-HaloSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU
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