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Product Name Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H139N11O27 Molecular Weight 1759
BC-Nor is a CLIP-tag substrate containing norbornene moiety for click chemistry applications
Product Name Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C52H71N11O20 Molecular Weight 1170
505 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-Exatecan Fmoc Product Name Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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