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membrane-impermeable Halotag ligand
S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616
Targeted protein degraders crowd into the clinic
838 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 522/546nm Solubility DMSO
TMP3-TMR Size:100nmol membrane-impermeable Halotag ligandThe TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP3 TMR is a third generation
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