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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) new Binfunctional carboxylic acid-carboxylic acid linker

SKU 4006007528
4.9
USD245.00 USD283.00

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Description

Binfunctional carboxylic acid-carboxylic acid linker

Product Name tert-butyl 2-[4-(2-aminoethyl)piperazin-1-yl]acetate Synonyms CAS Number n/a Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

Product Name Lenalidomide-C1-acid Synonyms Lenalidomide-4'-C1-acid CAS Number 2103656-92-2 Related CAS Molecular Formula C15H15N3O5 Molecular Weight 317

031 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) new Binfunctional carboxylic acid-carboxylic acid linkerSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established

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