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MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg 35 SMILES COC1=C(OC)C=C2CN(CC2=C1)C(=O)C1=C(SC2=C(Cl)C=CC=C2Cl)C=C(NC1=O)C(F)(F)F Purity (HPLC)

SKU 39742308020
4.6
USD495.00 USD522.00

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Description

35 SMILES COC1=C(OC)C=C2CN(CC2=C1)C(=O)C1=C(SC2=C(Cl)C=CC=C2Cl)C=C(NC1=O)C(F)(F)F Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

BG-TCO is a SNAP-tag substrate containg TCO moiety for click chemistry chemistry applications

Product Name Phthalimidinoglutarimide-propargyl-PEG1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG1-OH CAS Number n/a Related CAS Molecular Formula C18H18N2O5 Molecular Weight 342

Product Name Thalidomide-O-acetamido-PEG1-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-PEG1-C2-amine HCl CAS Number 2204226-02-6 Related CAS 2022182-59-6 (free base) Molecular Formula C19H23ClN4O7 Molecular Weight 454

MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg 35 SMILES COC1=C(OC)C=C2CN(CC2=C1)C(=O)C1=C(SC2=C(Cl)C=CC=C2Cl)C=C(NC1=O)C(F)(F)F Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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