Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Size:50mg Sticking It to Cancer with

Sticking It to Cancer with Molecular Glue for SHP2

Product Name tert-butyl 3-[2-(piperazin-1-yl)ethoxy]propanoate Synonyms CAS Number n/a Related CAS Molecular Formula C13H26N2O3 Molecular Weight 258

Product Name 3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propanoic acid Synonyms CAS Number 242459-97-8 Related CAS Molecular Formula C12H22N2O4 Molecular Weight 258

Datasheet        MSDS

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Size:50mg Sticking It to Cancer withSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as