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CA-SS-TMR is a cleavable HaloTag ligand featuring a disulfide bond that can be cleaved using a reducing agent
ACS Chemical Biology
CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
066 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:25mg CA-SS-TMR is a cleavable HaloTagSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para
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