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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE deuterium-labeled-heterocycle Excitation maximum = 444 nm

SKU 36236058285
4.8
USD495.00 USD542.00

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Description

Excitation maximum = 444 nm

Product Name: Cy3 alkyne monosulfo Synonyms: Cy3 alkyne

21 Purity (HPLC) >= 95% Solubility DMSO

907 Purity (HPLC) >= 95% Solubility DMSO

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE deuterium-labeled-heterocycle Excitation maximum = 444 nmSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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