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with a Kd value of 69 nM towards DCAF1 measured by fluorescence polarization
Product Name Thalidomide-O-acetamido-C3-amine HCl Synonyms Thalidomide-4'-O-acetamido-C3-amine HCl CAS Number 2565805-08-3 Related CAS 2022182-57-4 (free base) Molecular Formula C18H21ClN4O6 Molecular Weight 424
Product Name Phthalimidinoglutarimide-5'-propargyl-OH Synonyms CAS Number 2229725-43-1 Related CAS Molecular Formula C16H14N2O4 Molecular Weight 298
394 SMILES OC(=O)C(F)(F)F
Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4) Size:50mg with a Kd value ofSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived
