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526 SMILES O=C1N(CC2=C(NCCOCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
BC-PhN3 is a CLIP-tag substrate containg a phenylazide group for click chemistry applicatoions
Product Name DOTA-pentyne Synonyms CAS Number n/a Related CAS Molecular Formula C21H35N5O7 Molecular Weight 469
Product Name MC-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C68H89FN8O20 Molecular Weight 1357
MC-Val-Ala-PAB(m-PEG8)-Exatecan ca 526 SMILES O=C1N(CC2=C(NCCOCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
