SHP099 deuterium-labeled-carboxylic acid Product Name Pomalidomide-CO-PEG1-C2-Cl Synonyms Pomalidomide-4'-CO-PEG1-C2-Cl

Product Name Pomalidomide-CO-PEG1-C2-Cl Synonyms Pomalidomide-4'-CO-PEG1-C2-Cl CAS Number n/a Related CAS Molecular Formula C18H18ClN3O6 Molecular Weight 407

068 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCC(=O)N2CC3=C(C=CC=C3)C#CC3=C2C=CC=C3)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

4-(4-piperidinyl)-

SHP099 deuterium-labeled-carboxylic acid Product Name Pomalidomide-CO-PEG1-C2-Cl Synonyms Pomalidomide-4'-CO-PEG1-C2-ClSHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula