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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg 473 SMILES O=C1N(CC2=C(NCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC)

Description

473 SMILES O=C1N(CC2=C(NCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C36H56N4O11S Molecular Weight 752

S)-AHPC-CO-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C31H45N7O7S Molecular Weight 659

DBCO has been extensively used in copper-free click chemistry

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg 473 SMILES O=C1N(CC2=C(NCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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