DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg HaloTag SiR Ligand

HaloTag SiR Ligand

68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Cy3-CA CAS Number Related CAS Molecular Formula C40H57ClN3O3 Molecular Weight 663

161 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg HaloTag SiR LigandSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing