Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:25mg Product Name Thalidomide-C3-Br Synonyms Thalidomide-4'-C3-Br

Product Name Thalidomide-C3-Br Synonyms Thalidomide-4'-C3-Br CAS Number n/a Related CAS Molecular Formula C16H15BrN2O4 Molecular Weight 379

Product Name 3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propanoic acid Synonyms CAS Number 242459-97-8 Related CAS Molecular Formula C12H22N2O4 Molecular Weight 258

to enhance aqueous solubility

221 SMILES [2H]C([2H])([2H])OC1=CC=C(CC(=O)OC)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:25mg Product Name Thalidomide-C3-Br Synonyms Thalidomide-4'-C3-BrSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from