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a reaction where tetrazine compounds react with strained dienophiles
Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CAS Number 819869-77-7 Related CAS Molecular Formula C32H55N5O10 Molecular Weight 669
HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins
Product Name tert-butyl 3-[4-(piperidin-4-yl)piperazin-1-yl]propanoate Synonyms 1-Piperazinepropanoic acid
Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Size:5mg a reaction where tetrazine compoundsSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
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