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DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload 5(6)-FAM PEG3 azide is an

SKU 19155469465
4.7
EUR445.00 EUR484.00

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Description

5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

where multiple targets can be visualized simultaneously

Product Name DOTA-PEG2-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C29H47N7O12 Molecular Weight 685

Product Name Thalidomide-5'-propargyl-PEG1-OH Synonyms CAS Number n/a Related CAS Molecular Formula C18H16N2O6 Molecular Weight 356

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload 5(6)-FAM PEG3 azide is anSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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