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Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg 173 SMILES [2H]C([2H])([2H])OC1=CC=CC(N)=C1 Purity (HPLC)

SKU 18485205746
4.7
USD445.00 USD495.00

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Description

173 SMILES [2H]C([2H])([2H])OC1=CC=CC(N)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

resulting in turn-on fluorescence

S)-AHPC-CO-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C29H44Cl2N6O4S Molecular Weight 643

For research use only

Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg 173 SMILES [2H]C([2H])([2H])OC1=CC=CC(N)=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers

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